解剖学和形态学
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听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
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医学实验室技术
医学,全科和内科
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神经系统科学
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整形外科学
耳鼻喉科学
病理学
儿科学
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药理学和药剂学
生理学
基本医疗保健
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热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::During the past two decades, the phenomenon of hormesis has gained increased recognition. To promote research in hormesis, a sound statistical quantification of important parameters, such as the level and significance of the increase in response and the range of concentration where it occurs, is strongly needed. Here,...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/05-014r.1
更新日期:2005-12-01 00:00:00
abstract::The development of sensitive, biologically based indicators of contaminant exposure (i.e., biomarkers) is an ongoing topic of research. These indicators have been proposed as a first-tier method of identifying contaminant exposure. The primary objective of this research was to implement a biomarker-based method of exp...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/05-137r.1
更新日期:2005-12-01 00:00:00
abstract::The desorption behavior of benzidine from Lake Macatawa (Holland, MI, USA) sediment was investigated in this study using batch solvent extraction method. Seven solvents were tested as the extracting reagents: Deionized water (DI), calcium chloride in DI (CaCl2), sodium hydroxide in DI (NaOH), acetonitrile (ACN), a mix...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/05-017r.1
更新日期:2005-12-01 00:00:00
abstract::We examined the effects of multigenerational exposure of mercury (Hg) on Hg toxicity and biokinetics in a population of Daphnia magna. After chronic Hg exposure at 3.8 microg Hg/L, the first generation (F0) adults had an elevated 24-h median lethal concentration (LC50) of Hg (76 microg/L) when compared to the control ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/05-085r.1
更新日期:2005-11-01 00:00:00
abstract::Ionic silver is toxic to aquatic organisms at low concentrations. However, complexation to binding sites on natural organic matter has been shown to reduce silver toxicity. Research indicates that there is a need to develop reliable methods for characterizing silver binding at very low silver ion concentrations where ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-577r.1
更新日期:2005-11-01 00:00:00
abstract::Prior to the implementation of any new technology, possible environmental and health repercussions first must be researched. Fullerenes are to be produced soon on an industrial scale, with applications quickly following. To investigate the possible environmental impact of fullerenes, a C60-water suspension (nano-C60) ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-649r.1
更新日期:2005-11-01 00:00:00
abstract::Methods for the assessment of ecological risks associated with exposure to defined mixtures of toxicants are reviewed and formalized for single-species toxicity. Depending on the modes of action of toxicants in a mixture, these methods apply either the model for concentration additivity (CA) or the model for response ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章,评审
doi:10.1897/04-639r.1
更新日期:2005-10-01 00:00:00
abstract::Hexanitrohexaazaisowurtzitane (CL-20), a new polycyclic polynitramine, has the same functional nitramine groups (N-NO2) as the widely used energetic chemicals hexahydro-1,3,5-trinitro-1,3,5-triazacyclohexane (royal demolition explosive [RDX]) and octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (high-melting explosive...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/054-188r.1
更新日期:2005-10-01 00:00:00
abstract::The present study investigated new or lesser-studied and legacy organochlorine (OC) contaminants and metabolites in plasma and eggs of glaucous gulls (Larus hyperboreus) collected from major breeding colonies on Bear Island in the Norwegian Arctic. Hexachlorobutadiene was below the method limit of detection (< 0.07 ng...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/05-067r.1
更新日期:2005-10-01 00:00:00
abstract::An original species-selection method for the building of test batteries is presented. This method is based on the statistical analysis of the biological and ecological trait patterns of species. It has been applied to build a macroinvertebrate test battery for the assessment of sediment toxicity, which efficiently des...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-559r.1
更新日期:2005-09-01 00:00:00
abstract::In our study, we aim to characterize the estrogenicity of 18 independent rivers that receive effluent from sewage treatment works. During the winter and summer of 2003, we collected multiple water samples and measured environmental estrogens with an in vitro yeast-based reporter gene assay; estrogenicity was expressed...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-305r.1
更新日期:2005-09-01 00:00:00
abstract::In the present study, electron paramagnetic resonance coupled with spin-trapping technique was used, with alpha-phenyl-N-tert-butylnitrone (PBN) as a spin-trapping agent, to investigate free radical generation in freshwater fish with acute 2,4-dichlorophenol (2,4-DCP) poisoning. The PBN-radical adducts were detected i...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-640r.1
更新日期:2005-09-01 00:00:00
abstract::In Australia, the collection of estuarine invertebrates from the field for whole-sediment toxicity tests is hindered because of temporal variability in their population densities and distributions. The present study aimed to develop culturing procedures for Melita plumulosa (Zeidler), an epibenthic and intertidal, dep...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-409r1.1
更新日期:2005-08-01 00:00:00
abstract::This work describes the uptake of two organochlorine pesticides from slow-release pellets by largemouth bass and the utility of a blood plasma enzyme-linked immunosorbent assay (ELISA) method for exposure verification. We measured blood and tissue levels by gas chromatography/mass spectrometry and by a novel ELISA met...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-492r.1
更新日期:2005-08-01 00:00:00
abstract::A series of atomistic simulations was performed to assess the ability of the Schulten dissolved organic matter (DOM) molecule, a well-established model humic molecule, to reproduce the physical and chemical behavior of natural humic substances. The unhydrated DOM molecule had a bulk density value appropriate to humic ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-567r.1
更新日期:2005-08-01 00:00:00
abstract::We evaluated the influence of waterborne and dietary lead (Pb) exposure on the acute and chronic toxicity of Pb to the amphipod Hyalella azteca. Test solutions were generated by a modified diluter with an extended (24-h) equilibration period. Acute (96-h) toxicity of Pb varied with water hardness in the range of 71 to...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-480r.1
更新日期:2005-07-01 00:00:00
abstract::Phytochelatins are small, intracellular, metal-binding polypeptides produced by algae on exposure to increased metal concentration in their environment. The aim of the present study was to examine the relationship between phytochelatin concentration, bioaccumulated metal, and sensitivity of algal growth on cadmium exp...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-394r.1
更新日期:2005-07-01 00:00:00
abstract::Rainbow trout embryos and larvae were exposed to 0, 0.1, and 1 microg/L total silver (as AgNO3) in water of three different hardnesses (soft water [2 mg/L as CaCO3], moderately hard water [150 mg/L], and hard water [400 mg/L]) in a flow-through system from fertilization to swim-up (64 d). The objective of the study wa...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-056r.1
更新日期:2005-07-01 00:00:00
abstract::The median 96-h lethal zinc concentration (LC50) was 439 microg Zn/L (hardness of 154 mg/L as CaCO3) for feral mottled sculpin (Cottus bairdi), decreasing to a median incipient lethal level of 266 microg Zn/L after 13 d. The 30-d chronic value was 255 microg Zn/L. The acute toxicity-hardness (ln-ln) slope of 1.022 exc...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-235r.1
更新日期:2005-06-01 00:00:00
abstract::The high incidence of intersex roach (Rutilus rutilus) in some United Kingdom rivers that has been associated with exposure to sewage treatment works (STWs) effluent led us to hypothesize that top predator fish also may be affected by estrogenic chemicals, because they are likely to bioaccumulate lipophilic compounds ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-447r.1
更新日期:2005-06-01 00:00:00
abstract::Atrazine (2-chloro-4-ethylamino-6-isopropylamino-s-triazine) and its degradation products are important contaminants of world water systems and have effects on aquatic life. These effects are modulated by the degradation of atrazine, which depends, in part, on its reactivity with soil minerals. We have studied the deg...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-248r.1
更新日期:2005-06-01 00:00:00
abstract::Many habitats may be exposed to multiple chemical contaminants, particularly in agricultural areas where fertilizer and pesticide use are common; however, the singular and interactive effects of contaminants are not well understood. The objective of our study was to examine how realistic, sublethal environmental level...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-319r.1
更新日期:2005-05-01 00:00:00
abstract::Atrazine is a herbicide used most frequently in North America, but it usually is encountered in mixtures of agrochemicals. Few atrazine exposure studies have been conducted using mixed pesticides; therefore, little data are available to suggest reliable means of discerning effects attributable to atrazine. The common ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-007r.1
更新日期:2005-05-01 00:00:00
abstract::The effects of elevated plasma cortisol levels on vitellogenin (VTG) induction were examined in the fathead minnow (Pimephales promelas) in an attempt to evaluate the potential influence of stress on this commonly used biomarker of estrogenicity. Two separate experiments were conducted in which fish plasma cortisol wa...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-309r.1
更新日期:2005-05-01 00:00:00
abstract::We describe a highly selective and sensitive method for determination of estrone (E1) and beta-estradiol (E2) in sediments, using high-performance liquid chromatography/time-of-flight (HPLC-ToF) mass spectrometry. The method involved sequential cleanup of sediment extracts over solid phase extraction cartridges, norma...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-167r.1
更新日期:2005-05-01 00:00:00
abstract::We raised embryos and tadpoles of green frogs (Rana clamitans melanota) and leopard frogs (R. pipiens) in situ along a contamination gradient in the Fox River/Green Bay ecosystem (WI, USA). Differences in exposure were reflected by significant positive regressions between concentrations in sediment and in frogs of pol...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-213r.1
更新日期:2005-04-01 00:00:00
abstract::Recently we showed that tetracyclines tend to persist and may accumulate in sandy soils after repeated fertilizations with liquid manure. We continued these field investigations from 2001 to 2003 and observed no further accumulation of tetracyclines in soil, but found that the average tetracycline concentration remain...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-182r.1
更新日期:2005-04-01 00:00:00
abstract::Antibiotics are used to maintain healthy livestock and to promote weight gain in concentrated animal feed operations. Antibiotics rarely are metabolized completely by livestock and, thus, are often present in livestock waste and in waste-treatment lagoons. The introduction of antibiotics into anaerobic lagoons commonl...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-093r.1
更新日期:2005-04-01 00:00:00
abstract::In this study, biphenyl-2,2',6,6'-tetracarbaldehyde, an initial byproduct formed from the ozonation of pyrene, and biphenyl-2,2',6,6'-tetracarboxylic acid, a subsequent pyrene ozonation byproduct, were evaluated using two toxicology assays to compare the toxicity of ozonation byproducts with that of the parent compoun...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-679.1
更新日期:2005-03-01 00:00:00
abstract::Total mercury (Hg) concentration was determined in several piscivorous and nonpiscivorous species of fish from 38 drainage lakes with clear-cut, burnt, or undisturbed catchments located in the Canadian Boreal Shield. Mercury concentrations increased with increasing fish trophic position as estimated using stable isoto...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-065r.1
更新日期:2005-03-01 00:00:00
abstract::Locomotor behavior in terrestrial organisms is crucial for burrowing, avoiding predators, food seeking, migration, and reproduction; therefore, it is a parameter with ecological relevance. Acetylcholinesterase (AChE) is a nervous system enzyme inhibited by several compounds and widely used as an exposure biomarker in ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-131r.1
更新日期:2005-03-01 00:00:00
abstract::Because fish represent the principal methylmercury (MeHg) pool in the water column of freshwater systems, MeHg released from their carcasses could represent an important flux to the environment. Necrophagous invertebrates such as fly larvae can play an important role in this Hg recycling. We studied Hg accumulation by...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-054r.1
更新日期:2005-03-01 00:00:00
abstract::Species sensitivity distributions (SSD) were constructed using acute toxicity data of various cladoceran species collected in five different aquatic systems. The aim of this research was to study the relative acute cladoceran community sensitivity in different aquatic systems. Current risk assessment procedures are ba...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/03-067r.1
更新日期:2005-02-01 00:00:00
abstract::The bioconcentration and elimination of avermectin B1 in sturgeon muscle were investigated with high-performance liquid chromatography. Mean concentrations of 0.2 and 1 ng x ml(-1) in water were maintained for a 22-d exposure period. The concentrations of avermectin B1alpha in muscle tissues reached steady state withi...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/03-480.1
更新日期:2005-02-01 00:00:00
abstract::Rice is the main crop in the subbasin of the fluvial lagoon system of Palizada River (FLSPR) in the state of Campeche, Mexico. The pesticides used to control pests of this crop mainly are carbofuran, chlorpyrifos, and glyphosate. Black-bellied whistling duck (Dendrocygna autumnalis) is an ecologically and economically...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/03-646.1
更新日期:2005-02-01 00:00:00
abstract::To investigate possible relationships between polychlorinated biphenyl (PCB) exposure and infectious disease mortality in harbor porpoises (Phocoena phocoena) in United Kingdom waters, summed blubber concentrations of 25 chlorobiphenyl congeners (sigma25CB) in healthy harbor porpoises that died of acute physical traum...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/03-663.1
更新日期:2005-01-01 00:00:00
abstract::We conducted a seasonal study of the uptake of Cd, Se(IV), and Zn by natural phytoplankton assemblages collected from two locations in Hong Kong coastal waters. Marine phytoplankton in Port Shelter was dominated by diatoms and cyanobacteria, while phytoplankton in Tolo Harbour was dominated by dinoflagellates. The nat...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/04-125r.1
更新日期:2005-01-01 00:00:00
abstract::Field populations of aquatic organisms, particularly those inhabiting flowing waters, likely are exposed to short pulses of pesticides following periods of spray drift, surface runoff, or drain flow. In the present study, we investigated the effect of pulse exposures of a pyrethroid insecticide, esfenvalerate, on surv...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/03-547.1
更新日期:2005-01-01 00:00:00
abstract::Analysis of sperm has been investigated as a possible method to examine the toxicity of environmental contaminants. The amphibian sperm inhibition toxicological test (ASITT) method examines the effects of contaminants on Xenopus laevis (African clawed frog) sperm motility and path trajectories. As part of a preliminar...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/03-573.1
更新日期:2004-12-01 00:00:00
abstract::Determination of the most sensitive and susceptible organismal life stage is important for use of the organism in toxicity assessments of environmental pollutants. In the present study, the sensitivities and susceptibilities of larval developmental stages of two black fly sibling species, Simulium vittatum Zetterstedt...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/03-657.1
更新日期:2004-12-01 00:00:00